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Loss of melanin pigmentation may be caused by the absence of melanocytes, as in vitiligo; reduced or absent synthesis of melanin by melanocytes, as in albinism and phenylketonuria; abnormal packaging of melanin in melanosomes, as in the Chediak-Higashi syndrome; or insufficient transfer of melanosomes to keratinocytes, as in hypopigmentation secondary to atopic dermatitis or psoriasis.
Low motivation leads to the insufficient transfer of knowledge, the underutilization of available resources, and weak health-care system performance [ 40, 41].
This could be due to an insufficient transfer of electrons from Pdx to the P450 as CYP154H1 and CYP101A1 (the natural monooxygenase partner of PdR and Pdx) share only 26% sequence identity on protein level.
The potential for mechanisms such as HFMCs to meet their goals has been limited by wider decentralisation challenges such as insufficient transfer in practice of decision-making power to local levels for a range of functions, lack of clarity in responsibilities at local levels, and broader factors such as the prevailing political context, and inadequate access to financial resources [ 8- 10].
This difference of degradation rate between both groups may be due to the reduced pH values caused by the insufficient transfer of metabolic wastes that likely promoted the degradation of the scaffolds in the PGA group [ 34, 35], which in turn led to islet aggregation without the support of the scaffolds and decreased islet survival.
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But the OGE's response found this insufficient: "Transferring operational control of a company to one's children would not constitute the establishment of a qualified blind trust, nor would it eliminate conflicts of interest under 18 U.S.C. § 208 if applicable".
The minutes also warned that if a joint venture company were to be created, there might be "insufficient risk transfer to the PSP [private sector partner]" as well as a "significant risk of industrial action".
This decrease was due to insufficient oxygen transfer rate.
Reactor runaway occurs when an exothermic reaction takes place in a reactor with insufficient heat transfer area.
An incorrectly dimensioned heating system leads to insufficient heat transfer and, in combination with inadequate agitation, finally to foam formation [31].
In addition, the voids (Fig. 7c) can be formed due to the removal of the trapped solvent by the insufficient mass transfer during drying process [8, 32, 33].
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