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When the reactive power capabilities are insufficient to regulate the voltage, a coordinated solution with an OLTC distribution transformer or an active power curtailment, as a last option, may be the solution.
Although in our exerimental setting PLD2 inhibition tended to decrease S6K1 phosphorylation, and thus mTORC1 activity, this did not significantly affect myotube size, suggesting that the impact of PLD2 activity on mTOR is insufficient to regulate downstream pathways.
However, such IL-10 induction may be insufficient to regulate proinflammatory cytokine expression in RA, because the addition of exogenous IL-10 to ST cell cultures markedly reduced TNF-α and IL-1 production [ 13, 15].
This is in agreement with additional data suggesting that HY5 alone is insufficient to regulate transcription, and that HY5 can act as both a positive and a negative regulator (Lee et al, 2007).
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"When chemical interests may face additional requirements, the bill gives them so many ways to evade or challenge them, that it reduces the Environmental Protection Agency's already insufficient authority to regulate toxic chemicals".
Furthermore, transiently transfecting the BRCA1 proximal promoter construct L6 resulted in a reduction in its activity by approximately 50% in shGR-19 cells compared to EV-50 cells in the absence of HC, indicating that the level of endogenous GR in these cells is insufficient to positively regulate BRCA1 expression.
There are also insufficient industrial guidelines to regulate the selection and application of these coatings.
Consistently, siLmna-p14arf cells remained refractory to p16ink4a suggesting that the cells had insufficient pRB function to regulate the cell cycle (Figure 5B).
In contrast, lower levels of wild-type ERα in the weakly ERα-positive breast tumors are inhibited to a greater extent by the presence of ERΔ7, leaving the tumor cells with insufficient ERα activity to regulate ERα target gene expression and thus with a Basal phenotype (Fig. 4, left).
Phosphosite mutations caused Separase deregulation exclusively in PGCs [28] and early embryonic cells [29] because they contain insufficient amount of Securin to regulate Separase.
If someone exercises vigorously on a hot day with insufficient water intake, the body's ability to regulate temperature can be affected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com