However, the key factor controlling this sludge pretreatment process, pH, has received insufficient attention to date.
This suggests that drugs targeting enzymes may potentially affect a greater number of species than a drug targeting a receptor, although there are insufficient studies to date to provide convincing evidence for this in practice.
Although there are currently no evidence-based guidelines on the use of MBIs for improving sleep in cancer patients, presumably due to insufficient evidence to date, it is encouraging to see renewed interest in the use of MBIs for cancer-related sleep difficulties since the first sleep outcomes of a 6-week MBSR program in cancer patients were published in 2003.
There are insufficient studies published to date to assess the effects of lags and duration of exposure.
There is insufficient data published to date on the effects of autologous MSC on knee cartilage defects.
These are likely to be among the reasons for insufficient progress made to date, as interventions rarely reach all population groups in equitable ways.
The small but significant positive correlation of overview item QI – present QoL with total T levels may be a preliminary indication of construct validity, but there is insufficient research evidence to date to support a link between T levels and QoL.
The Government Accountability Office, the research arm of Congress, wrote in the report that ground-based missile defense system testing, "to date, was insufficient to demonstrate that an operationally useful defense capability exists".
Although many advances have been made in understanding particular mechanisms involved, they have, to date, proved insufficient to provide real breakthroughs in this area of tuberculosis research.
HIV-positive patients have unpredictable local immune responses even with severe systemic immunosuppression and data reported to date is insufficient to predict the effect of imiquimod in HIV-positive patients.
