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Although well established in cell lines and today frequently used in transgenic mouse strains, certain limitations apply to these systems, mainly insufficient tightness of gene-repression and/or moderate induction levels, e.g., due to ineffective delivery and targeting of agonists to the cell type/tissue of interest, as well as stochastic epigenetic transgene silencing [4] [5].
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Intermittent claudication is defined as the painful aching, cramping, or tightness of muscles during exercise, due to insufficient blood flow to meet the metabolic demands.
A study by In et al. (2009) showed that an insufficient tibial slope was an independent risk factor for flexion gap tightness.
Cerebral palsy can manifest as severe tightness of certain muscle groups resulting in limited movement or insufficient tonus of the muscles, also leading to greater or lesser limitations in movement.
However, it can only be introduced in the most airtight dwellings (and few current dwellings come close to the required levels of air tightness), pressure differentials may in some circumstances exacerbate radon levels, 42 and, as yet, experience with it has been insufficient to know how well it would work in practice over the long term.
Stopping times and tightness.
LeBron has real tightness.
Tightness in the chest.
There is chest tightness.
And muscle tightness?
Tightness in the throat.
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CEO of Professional Science Editing for Scientists @ prosciediting.com