Because growth was insufficient for susceptibility testing, the presence of MAP was assumed; however, the assumption was made after 2 years, because of difficulties in isolating MAP from human specimens (e.g., blood) in media not thought to enable its growth.
If growth was insufficient, drug-susceptibility testing was performed by using the modified proportion method in BACTEC 460TB (Becton-Dickinson).
Although necessary, expression of CAT-1 is insufficient to confer susceptibility to EcoHIV replication.
Although the dominant genetic factor is the MHC in both RA and PGIA, the MHC alone is insufficient to affect arthritis susceptibility and severity (for example, in H-2d DBA/2 mice) [ 9].
Again, to what extent this may indicate less susceptibility and insufficient depletion of memory B-cell subsets in association with no response or with a shorter response is not known.
Taken together, this suggests that disuse of antibiotics, to which microorganisms have developed resistance, is insufficient to confer complete susceptibility to the antibiotics as the burden of resistance may or may not result in enough fitness cost to revert resistant strains back to susceptible strains after antibiotics disuse.
Because these animals maintained higher blood levels of DA, Xi et al. (1997) proposed that susceptibility resulted from insufficient renal clearance of toxin.
Recent advances in GWAS have substantially improved our understanding of the pathophysiology of diabetes, but the currently identified genetic susceptibility loci are insufficient to explain differences in diabetes risk across different ethnic groups or the rapid rise in diabetes prevalence over the past several decades.
It is possible that the R337H mutation in combination with these polymorphisms and possibly other genetic alterations creates a p53-insufficient state that enhances tumor susceptibility.
Nevertheless, the mixtures made with RA may have insufficient durability due to their high susceptibility to water action which was evaluated using stripping tests.
