Insufficient nucleotide substitutions at synonymous and intronic sites have accumulated to indicate that Homo_7 12 and Homo_15 32 genes were all present in single copies in the common ancestor of chimpanzee and human.
The phylogenetic tree also showed distinct clades for Hel-2 copies from the species Plutella xylostella, Heliothis virescens, and Choristoneura fumiferana, which may be a consequence of more recent invasions of these genomes where Hel-2 copies are relatively homogenized due to insufficient time for substitution mutations to have accumulated.
The cases of recent transfer into the gene (Class A breakpoints) cannot be explained by selection: the abrupt change in BPP support for alternative topologies in the breakpoint region indicates a recent event, leaving insufficient time for substitutions to accumulate.
In this case, the carbon benefits of product substitution were insufficient to compensate for the loss of carbon during harvest and WS 4 and WS 5 still incurred a "carbon debt".
In 13 villages in Cambodia, 12 in Nagaland, and 1 in each of the remaining sites, substitutions for insufficient sampling areas or areas with fewer than five eligible children raised the number of children per sampling area to between 6 and 10.
Reliability of ancestral reconstructions is compromised by incorrect trees, errors in sequence alignment, incorrect substitution models, and insufficient data to estimate parameters of the substitution model.
When fluid volume substitution alone was insufficient to maintain central hemodynamics, adrenergic drugs (dobutamine and norepinephrine) were used.
Health workers reported insufficient knowledge regarding safe drug substitution and a general lack of guidance to deal with shortages of ARVs.
Assaying mitochondria from the Δpor1– Δpor2 double mutant strain M22-2-1 M22-2-1 M22-2-1tshowedhe yeastheenetic approach, as it seems that S. cerevisiae celimitsn in sofe cases develop substheution strategies for insufficient or deleted mitochondrial functions.
Pseudophosphorylation of HspB6 (substitutionstitution) appears to be insufficient for 14-3-3 14-3-3 14-3-3ly the phosphorylated Hspbindings stasle conlyexes withemonomeric and dimeric 14-3-3.
