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In Pairs E and I, PCR reactions with specific primers were unsuccessful due to insufficient specificity.
However, due to insufficient specificity and sensitivity of prostatic acid phosphatase [ 13], prostate-specific antigen (PSA) was the gold standard for prostate cancer diagnostics in clinic for a long time.
For a technical reason (insufficient specificity), the result of v-rDNA I+II was not repeated with real-time PCR (not shown).
The disagreement is most likely due to insufficient specificity of the antibodies used in previous studies.
Most available drugs suffer from insufficient specificity toward tumor cells [ 2].
Insufficient specificity (cross-reactivity), interference phenomena and poor robustness remain weak points.
Similar(30)
These previous methodologies have several limitations such as poor reaction efficiency and low yields, limited choices of protein reagents (e.g., specific DNA modifying proteins), and insufficient site specificity in respect to the cross-linking site within the protein.
These positive results could have resulted from insufficient test specificity or from individual infections that escaped prior detection.
This study indicated that an insufficient cultural specificity had resulted in improper and disconnected knowledge translation (54).
Common theoretical challenges include insufficient construct specificity, examining cognitive processes in isolation (without reference to other aspects of information processing), and interpreting cognitive processes as contributing to psychopathology when they may be mere epiphenomena of clinical problems.
Although clinical dysphagia screening is known to reduce the risk of pneumonia and fatal outcome after stroke [ 1- 3], this approach has an insufficient sensitivity, specificity and interrater reliability, and is particularly poor in detecting silent aspiration [ 4, 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com