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This effect is associated with insufficient responsiveness seen in a subgroup of PNH patients.
Insufficient responsiveness may be because these domains were designed to measure concepts that are not specifically related to subjective pain, although pain was previously shown to change during the course of raloxifene treatment and was assumed to represent an improvement in patient global assessment [ 16].
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This occurs despite evidence for increased maturation of B cells in NZB dTg mice, suggesting that entry into the mature B cell pool is insufficient to restore responsiveness to HEL in dTg B cells.
However, the 3D Matrigel system is still insufficient to reproduce the responsiveness of acquired tumor resistance.
The proliferation response to graded amounts of these antibodies was identical in both cell lines suggesting that increased signaling alone is insufficient to cause the increased responsiveness (37).
Quality, as envisioned in current policies and legislations, is more input-oriented with insufficient focus on outcome and responsiveness to patient's needs, like courteous behaviour by staff and explanation of diagnosis, treatment and drugs to patients.
Such a low responsiveness was clearly insufficient to detect DNA damage for exposures with 4.2- and 16.6-times lower Cr VI) levels in the 20 mg/L and 5 mg/L test groups, even in the implausible situation of no reduction and no dilution of Cr VI) in the stomach.
But those advantages are often insufficient in the face of decreased responsiveness, total lockout when you can't find a hotspot, and a dearth of applications that are good enough to replace the ones you've already learned.
In particular with respect to burnout, insufficient information about the defects in cortisol responsiveness and their potential spontaneous normalisation is available.
Consequently, insufficient caudate activation could result in cortical hyper-responsiveness, which may subjectively be experienced as hyper-arousal.
The available data is as of yet insufficient for construction of a mechanistic model of the responsiveness of breast cancer cell lines to growth factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com