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Insufficient protein can cause brittle nails.
Although insufficient protein and calories have been blamed, studies have not been able to pinpoint the exact causes.
Insufficient protein, caloric, and vitamin intake interferes with bone formation during growth and remodeling, directly because of an inadequate supply for matrix formation and indirectly because of a deficient production of crucial hormones and enzymes.
Kwashiorkor, a Ghanaian word meaning the disease that the first child gets when the new child comes, is typically seen when a child is weaned from high-protein breast milk onto a carbohydrate food source with insufficient protein.
Decreased levels of secondary production (e.g., a reduction in the fish population) can lead to a meagre harvest, which can in turn provide insufficient protein for some local human populations.
Of the patients with an albumin of <3.8 mg/dl (37% of sample), 73% were given a nutritional diagnosis of insufficient protein intake.
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Insufficient protein-folding capacity in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR).
For a haplo-insufficient protein, this may fit well with the different behaviour of a TC versus a SCLC.
The OPTIMEN trial was designed to assess in older men with moderate physical dysfunction and insufficient habitual protein intake (< recommended dietary allowance, RDA, 0.8 g·kg− 1·d− 1) the efficacy of consuming diets containing 163% RDA (1.3 g·kg− 1·d− 1) for protein, compared to RDA, to increase lean mass, muscle performance, and physical function.
When the MALDI-TOF-MS information is insufficient for protein identification, amino acid sequencing is necessary (47).
A major drawback of our data is the high amount of patients with insufficient urinary protein after extraction and dialysis.
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