Sentence examples for insufficient potency from inspiring English sources
Artificial flavourings are often used in food products because of the high cost, lack of availability, or insufficient potency of natural flavourings.
Yet their medicinal applications are hindered by insufficient potency for chemotherapy.
Unfortunately, the design of specific rhomboid inhibitors has lagged behind, and previously described small molecule inhibitors displayed insufficient potency and/or selectivity.
A recent NIH workshop on combination drug therapy for TBI concluded that past failures in clinical trials resulted, in part, from preclinical testing that selected drugs with insufficient potency [2].
Whether the method of implantation of the tumour or insufficient potency of rucaparib is responsible for the lack of effect has not been determined.
Although these cytotoxins worked well when administered as standard chemotherapy, they proved to have insufficient potency at low concentrations when conjugated to a mAb [ 161].
However, most of the reported radiotracers failed to visualize COX-2 in vivo due to multiple challenges including low metabolic stability, insufficient inhibitory potency and specificity for COX-2, and high non-specific binding to other targets.
These findings are consistent with insufficient drug potency and poor drug penetration into the CSF, and might suggest that the CNS served as a major site of viral replication in this subject.
Compound 42 gave some indication that TbNMT/ hNMT selectivity may be achievable within this series, although 42 itself had insufficient cellular potency to progress further and into in vivo efficacy studies.
Optimization of the assay resulted in increased sensitivity that at the moment is still insufficient for developing a potency assay for product release, but may be useful for evaluation of more concentrated samples.
Last, we recognize that better seizure suppression after the second, smaller, PTZ dose may reflect tDCS antiepileptic potency which is insufficient to overcome seizures triggered by high-dose PTZ, but adequate to suppress seizures triggered by a lower PTZ dose.
