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The cell surface expression of death receptor (DR 4 or DR5 is a prerequisite for TRAIL-mediated apoptosis, but is insufficient in case of blocked intracellular pathways.
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A single gene assessment requires high RNA quality from fresh (frozen) tissue, however, and might be insufficient in cases of more heterogeneous RNA quality (for example, RNA from paraffin-embedded tissues).
Various regularization methods are applied to improve performance in case of insufficient adaptation data.
Second, the actual interest payment may be smaller in case of insufficient cash flows.
Involving professional third parties in case of insufficient or underperforming crowd is important from this perspective.
This paper focuses on using various matrix regularization methods to improve the performance of the eigenphone method in case of insufficient amount of adaptation data.
In case of insufficient ST tendon thickness (less than 7 mm), then the gracilis tendon was also used [13].
In case of insufficient effect or unacceptable side effects, neurosurgical treatment using microvascular decompression or lesion treatment should be considered.
In case of insufficient or unavailable non-clinical data, the impact on the risk categorization should be evaluated.
In case of insufficient adjustment for confounding effect, it is likely that the intervention effect has been over-estimated.
In case of insufficient oxygen supply comparably poor conversions are observed while higher oxygen fluxes lead to increased methane conversions, especially in the presence of an efficient catalyst.
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