Of the 220 cases and 570 controls included in our previous study on Oncotype DX, there were 13 cases or controls with insufficient tumor for this study; an additional two controls became uninformative because their matched case had no tumor tissue.
Therefore, these methods are insufficient for the study of anti-cancer drug kinetics, which requires knowledge of concentration in deep tissue where tumors occur, and can only be measured in vivo.
Interactions relevant to the phase separation phenomenon occur over multiple length scales, from sub-nanometer to tens of micrometers, thereby making any single analytical technique insufficient for the study of phase separated macromolecular assemblies.
Because the radiosonde is normally released at intervals of 6 to 24 h, the temporal resolution of the soundings is insufficient for the studies of the detailed structure of mesoscale meteorological phenomena.
As this use of the AGREE instrument is new in social insurance medicine, we asked one expert in each country who had participated in developing several guidelines for a reaction to our results: "Are these correct in your view and what is your explanation for any insufficient scores?" This study was not submitted for ethical approval.
As the variables available for SES were insufficient in this study we have to interpret our results very carefully.
Not all eligible subjects were approached for enrollment because of insufficient manpower to commit specifically for this study at the different enrollment sites.
Moreover, some clinical specimens were insufficient for molecular study.
In total this dataset contains 137 interactions and was used to evaluate several structure-based classifiers of protein interaction types [ 13- 15]; however, it contains only 25 data points for human, yeast, and E. coli and is hence insufficient for our study.
Infants born at ≤30 week's gestation, who live within 200 km of the hospital to allow for follow up hospital appointments and home visits, and have English speaking families as there is insufficient funding for translators, are eligible for this study.
