Although there was insufficient enrollment for identification of an OBD, no dose-limiting toxicities were observed that limited eltrombopag dose escalation to 150 mg daily in the study.
Xia (1986) noted that the degree of constriction at the branch base was insufficient for species identification morphologically.
However, this was found to be insufficient for correct identification because the positions of the markings can vary among different wasps of the same species.
Paradoxically, the availability of Big Data makes data-driven computational approaches alone insufficient for biomarker identification.
The quality of the density is insufficient for accurate identification and assignment of a ligand.
When the MALDI-TOF-MS information is insufficient for protein identification, amino acid sequencing is necessary (47).
Otherwise there were only 21 deceased (2% of all study deaths) for whom our practice archives and those of the Health Authority were jointly insufficient for unambiguous identification.
Additionally, posttranslational modifications, e.g., glycosylation and phosphorylation, have to be considered, and thus only the mass is insufficient for protein identification [ 37].
However, despite sophisticated deconvolution algorithms [ 4, 5], the fragmentary information provided by splicing arrays is typically insufficient for unambiguous identification of full-length transcripts [ 6, 7].
This example demonstrates that in some cases MS and MS n characterization is insufficient for full identification of unknown bioactive compounds.
