Inherited diseases now known to be caused by telomerase defects include certain forms of a condition called "congenital aplastic anemia", in which insufficient cell divisions in the stem cells of the bone marrow lead to severe anemia.
To test whether this difference was due to insufficient cell divisions needed to reach steady state, we passaged cells four times in subcultures.
Insufficient dead-weight division of the 54 kN DWM has been reformed to enable 8-step calibrations, along with expansion of its capacity to 100 kN.
Boxer said the verification process is insufficient because the division "does not have a reputation up until to this point that is good enough".
Although the addition of S1P and LPA alone was insufficient to induce cell division, it was able to enhance β-catenin-mediated hiPSC-CM proliferation.
The official added that efforts to fight the pollution are undermined by insufficient funds and the division of responsibility between different municipal governments, as well as the state and federal level water and environmental bodies.
Although their numbers were insufficient for a new division, personnel from New Zealand were arriving in the various NZEF depots in Europe at a much higher rate than they were being lost from the division due to casualties and attrition.
However, data for the genotypes other than HPeV3 were insufficient to substantiate a division into individual clades.
Both men were concerned that they had insufficient aircraft for the complete division to take part while British pilots and infantry were not familiar with the Waco CG-4 gliders that were to be used.
On the other hand, in IL1403Δ claR, small amounts of cellobiose-derived metabolites, which are formed after cellobiose uptake via CelB and activity of different than BglS hydrolases, are insufficient for effective mutant cell division, resulting in the limited mutant's growth.
Insufficient availability of folate during cell division reduces the synthesis of thymidine, increases uracil misincorporation, and hampers DNA repair.
