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Among the shortcomings are time dependence, susceptibility to errors in scanner and dose calibration, insufficient correlation between systemic distribution volume and body weight, and, consequentially, residual inter-study variability of the arterial input function (AIF) despite SUV normalization.
Insufficient correlation between systemic distribution volume and body weight (leading to variants of the SUV approach using lean body mass (SUV l b m ) [4] or body surface area (SUV b s a ) [5] for normalization), and, consequentially, residual inter-study variability of the arterial input function (AIF) despite SUV normalization [6]. 3.
Susceptibility to errors in scanner calibration, Insufficient correlation between systemic distribution volume and body weight (leading to variants of the SUV approach using lean body mass (SUV l b m ) [4] or body surface area (SUV b s a ) [5] for normalization), and, consequentially, residual inter-study variability of the arterial input function (AIF) despite SUV normalization [6].
47 There could therefore be insufficient correlation between changes in drinking behaviour and alcohol consumption with patient-perceived impact on health status using this measure, which could have led to an underestimation of the QALY gains for nalmefene in this analysis.
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Although various CE-marked commercial kits are available, a recent comparison showed significant differences between kits and an insufficient correlation to the values of the 1st International Reference Preparation (Kennerkuecht et al. submitted).
The rules include: ① Rule 1 If the number of samples is sufficient, the distribution counting is strictly conducted on the corresponding data from questionnaires; ② Rule 2 If the number of samples is insufficient, the correlation between features is ignored and the independent distribution of the corresponding feature is used directly.
Although recently developed array-based technology has been applied to UCs (13– 18), the resolution of the arrays employed was insufficient or correlations between copy number alterations and the clinicopathological parameters of UCs were not analyzed in detail.
Insufficient understanding of the correlation between pump and pump as turbine (PAT) performance is a major problem encountered in the PAT selection and design.
Such a distribution of pathological stages and the high prevalence of Survivin expression might have rendered the power of this study insufficient to demonstrate any correlation between Survivin expression and specific pathological characteristics.
Up to now, there are few data from longitudinal studies on viral tropism in patients fully responding to HAART, and in particular, there are insufficient data on the correlation between viral tropism and combined HIV-proviral DNA, residual viraemia and drugs used in treatment.
To date, there are insufficient data to establish a correlation between SVF-dose, and direct therapeutic effect.
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