There were reports of late distribution of guidelines and insufficient copies, which restricted their ability to implement the policy: "The centre was so miserly to send only one guideline.
This can arise due to inherent bias in the amplification conditions (variable primer annealing, amplicon sequence content, suboptimal reaction temperature or salt concentration, etc)., or when initial template concentrations are insufficient to generate copy numbers exceeding the minimum detection threshold.
Such loans would be made only "in exceptional circumstances following a unanimous decision of euro area heads of state or government notably in case the E.S.M. capacity would prove insufficient," according to a copy of a draft statement from euro zone finance ministers that was circulating Thursday.
When the information on the differential molecular function of paralogs was insufficient, we chose the copy with a higher expression breadth.
The dominant LGI1 mutations in ADPEAF could be either haploinsufficient (one wild-type copy makes insufficient amounts of protein for proper function) or dominant negative (i.e. mutant LGI1 interferes with wild-type LGI1 or its binding partners).
Although recently developed array-based technology has been applied to UCs (13– 18), the resolution of the arrays employed was insufficient or correlations between copy number alterations and the clinicopathological parameters of UCs were not analyzed in detail.
Although they later split from Sanger over charges of insufficient support, Goldman and Reitman distributed copies of Sanger's pamphlet Family Limitation (along with a similar essay of Reitman's).
Poor socialization; Insufficient quantity of MTP copies at health facilities; Constraints to implementation at government health facilities; Central Medical Stores SAMESS) constraints in supporting implementation; No clear policy of involving private health facilities in the implementation.
Finally, the discriminatory power of IS 6110-RFLP typing is insufficient for those strains whose copy number of IS 6110 is 6 or less (the so-called low-copy strains are seen among M. bovis isolates from cattle or M. tuberculosis isolates from Asia) [ 53– 53].
Currently there is insufficient knowledge about exact 16S copy numbers to correct for this [ 36].
