The prospects of using these regulating metabolites depend on the "range", specificity and safety for other members of the microbial community in insufficient concentrations.
Insufficient concentrations were associated with early measurements (< 72 h from the sepsis' onset) (p = 0.035) and creatinine clearance increase (p = 0.01).
Ticks are obligately hematophagous, and the blood of their hosts may have insufficient concentrations of what for the tick are essential nutrients, such as amino acids, nucleosides, vitamins, and other enzyme co-factors.
This lack of effect may reflect insufficient concentrations of Ala-Ala reaching the BCSFB.
Accumulating evidence indicates that insufficient concentrations of circulating 25(OH D are associated with glucose intolerance, insulin resistance, metabolic syndrome, and increased risk for diabetes (2).
This results in dose-limiting side effects and insufficient concentrations of the drugs in the tumour, through which efficacy is limited and drug resistant cellular subpopulations may emerge.
About 10% of the spots contained insufficient concentrations of PCR product and were easily distinguishable from other spots using a SNR threshold of 3 (Supplementary Figure 2).
For insufficient concentrations, the RBCs settle to the bottom of the wells to form a small red area in the center when viewed from underneath.
The sources of this incomplete recovery were insufficient concentrations of oxidant in the absorbate, the deterioration of absorbate with time, and improper absorber designs.
Importantly, when drug monitoring is performed in ICU patients, β-lactam regimens were modified in most patients, either because of insufficient concentrations or antibiotic accumulation [ 54].
It is possible that the 0.5 mL saliva samples analyzed in this study contained a significant percentage of non-human DNA and were more likely to fail genotyping due to insufficient concentrations of human DNA.
