Meiser et al commented that it was not possible to include other outcomes of risk counselling, such as mammographic screening uptake, because of an insufficiency of studies; findings to date have been inconsistent (Kash et al, 1995; Audrain et al, 1999; Schwartz et al, 1999).
"Plant protein intake is associated with fibroblast growth factor 23 and serum bicarbonate levels in patients with chronic kidney disease: the Chronic Renal Insufficiency Cohort study". Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation 22, no. 4 (July 2012): 379-388.e1.
The role of reduced β-cell mass in human type 2 diabetes, the primary importance of β-cell apoptosis, and the insufficiency of replication/neogenesis have been studied by several authors using histological pancreatic samples, or isolated islets.
The main limitation of our study is insufficiency of result generalization at the population level.
Recruitment ended prematurely before target enrollment number (n=85) was reached, since the study underwent insufficiency of subjects who fulfilled the strict inclusion criteria.
As retrospective study, the insufficiency of the socioeconomic and environmental information, such as the crashes scenario, including road conditions, vehicle speed, full-face helmet, cord-injury symptoms, was considered as limitation in our study.
In the Cardiac Insufficiency Bisoprolol Study (CIBIS), 21% of patients treated with bisoprolol improved by ≥1 NYHA class.
General reasons for discrepancies between studies are insufficiency of sample size, age/gender/BMI/ethnic/racial differences, differences in prevalence of infectious agent in case and control groups, differences in immune response caused by specific ligand, differences in stratification, methods of diagnostics of cancer or chronic inflammatory conditions, genotyping methods, and chance.
Considering the insufficiency of CR analysis above, some studies have tried to identify crash characteristics at individual level, in an effort to predict crash risk on a real time basis [7, 8, 9].
