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RPS19, RPL11 and RPS24 insufficiency cause distinct cell cycle defects in DBA patients [ 11, 12].
How might protracted respiratory insufficiency cause somatic mutations and the nuclear genomic instability seen in tumor cells?
Evidence demonstrates that dysfunctional mitochondria, not oxygen insufficiency, cause cancer cells to produce inordinate amounts of lactic acid that impact on the treatment of cancer [ 24].
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Dear Sir, We appreciate the comments of Zhang and colleagues and agree that our review is not sufficient enough to suggest that vitamin D insufficiency causes headache.
ACL insufficiency causes deterioration of the physiologic roll-glide mechanism of the femorotibial joint and results in an increased anterior tibial translation as well as an increased internal tibial rotation.
Fetuses became hypertensive on days 2 to 4 of embolization, although this response was attenuated by day 5. Conclusions: Chronic severe placental insufficiency caused a reduction in amniotic fluid volume not attributable to reduced fetal urine production.
In reality, President Ford had end-stage coronary artery disease and severe aortic stenosis and insufficiency, caused by calcific alteration of one of his heart valves.
In addition, the GSK-3β insufficiency caused an increased bone mass in adult mice without other abnormalities.
Whether OPA1 insufficiency causes ETC dysfunction and induces augmented ROS generation is independent of its role in mitochondrial dynamics and apoptosis, as suggested in the C. elegans DOA model [44], requires furthering elucidation.
Finally, when we created the experimental osteoarthritis model by inducing instability in the knee joints of adult mice of wild-type and C/EBPβ+/− littermates, the C/EBPβ insufficiency caused resistance to joint cartilage destruction.
Ischemic mitral regurgitation is mitral insufficiency caused by myocardial infarction.
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