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Pharmacological management cannot substitute for adequate intensive care management of the respiratory and bulbar insufficiency associated with MC.
Distinct from the localized hypoxia due to inadequate blood supply noted in ischemia (e.g. due to inadequate NOS activity) DMD patients have a well-described ventilatory insufficiency associated with significant desaturation of arterial oxygen (from 95% to 74% during sleep time) and ensuing systemic hypoxia that would also be predicted to contribute to patho-physiology [28], [29].
In summary, he presented with adrenal insufficiency associated with HH.
This is a consequence of the severe renal insufficiency associated with plasma cell leukemia.
Although much less common, severe liver insufficiency associated with AN has been better investigated [ 49].
Therefore the extent of dPABP insufficiency associated with these phenotypes remains unclear.
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The reprogrammed cells retained the disease genotype of the adult cells and were stimulated to differentiate into motor neurons that displayed functional insufficiencies associated with spinal muscular atrophy.
When averaging the three model estimates, the correlation increases slightly, showing that a combination of models is able to rule out some of the insufficiencies associated with individual models.
It is likely that growth inhibition is attributable to metabolic causes arising from both oxygen delivery and mitochondrial insufficiencies associated with iron deficiency [ 14].
Collectively, complete miscarriages, missed miscarriages, recurrent miscarriages, threatened miscarriages and placental insufficiency associated or not with maternal hypertensive disorders affect more than 30% of clinical pregnancies in humans.
To examine whether vitamin D deficiency or insufficiency is associated with depression and whether vitamin D supplementation is an effective treatment for depression.
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