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The disease-specific instruments were further categorized into cancer-specific and breast cancer-specific instruments.
After narrowing down the most frequently used PROMS by setting the frequency arbitrarily at five, the resulting instruments were further analysed by the individual items within each instrument.
Adjusted for age and gender In recognition of OAB as a symptom complex, the two incontinence-specific instruments were further analysed using multivariable regression to examine the relationship between UI and QOL, while accounting for other key OAB symptoms (urinary frequency, urgency and nocturia), age, gender, and OAB treatment status.
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The necessity of adequate cut-off levels in developmental screening instruments are further strengthened by a survey among US pediatricians providing health supervision to children up to 35 months-of-age [ 19].
The principles contained in this instrument were further developed in 2003 by the International Declaration on Human Genetic Data (IDHGD), which sets out more specific rules for the collection of human biological samples and genetic data.
The instrument was further tested using structural equation modelling to examine the impact of crowding on commuters' stress and feelings of exhaustion.
The suggestions given on time to time basis were incorporated, and the instrument was further reviewed till all the reviewers were satisfied with the categorization of the questions and their appropriateness in the context of learning objectives.
The performance of the volume miniaturized SPE based biosensor coupled with the portable microcontroller based instrument was further evaluated by applying it for the measurement of mitochondrial cyt c release during cardiomyocytes apoptosis; the results are validated well with the commercial electrochemical analyzer and standard ELISA.
The instrument was further refined based on psychometric and bivariate analysis of these data.
The instrument was further revised based on the results of the pilot test.
c) Experts' review: The modified instrument was further reviewed by NF1 researchers and clinicians.
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