Preliminary reports suggest that PRM analyses exhibit performance characteristics (dynamic range and measurement variation) comparable to those of MRM analyses performed on triple quadrupole instruments, and it appears likely that further development will expand the scope of targeted peptide and protein quantitation.
Box 2 Focus group instrument, as it appears in English Key informant instrument 1.
A study in the Sept. 3 issue of Nature says the syrinx, the source of bird song, is a more complicated instrument than it appears.
Based on the comparison or our conceptual framework with the content of four existing instruments, it would appear that developing an IPF-specific measurement instrument is justified.
There are different types of validity, which include face validity (does the instrument measure what it appears to measure?), criterion validity (do scores correlate with other measures of the behavior being studied?), construct validity (does the instrument make accurate predictions about behavior?), and discriminative validity (does the instrument accurately categorize different groups?) [50].
While most of the existing instruments are research projects themselves, it appears that the relevant technologies are maturing so that commercially available instruments may not be too far in the future, making this remarkable imaging modality widely available.
It appears the instrument was easy to complete, and this may have assisted with the good response rate.
Face validity is a simple indication that, on the face of it, the instrument appears to be measuring the desired conceptual domains.
Moreover, as the following will show, defining it only in terms of policy instruments appears unsustainable while defining it in terms of a public philosophy implies that the field has had a too narrow policy focus.
Given the high correlation between instruments, each of the HRQOL instruments appears acceptable apart from the EQ-VAS which exhibited low correlation with the others.
