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While targeted experiments are routinely performed on triple quadrupole instruments in selected reaction monitoring (SRM; often referred as multiple reaction monitoring, MRM) mode, the quadrupole-orbitrap mass spectrometers allow quantification in MS/MS mode, also known as parallel reaction monitoring (PRM).
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GC analyses were carried out using a GC-QqQ-MS instrument in selected reaction monitoring (SRM) acquisition mode which has allowed the achievement of high specificity by selecting appropriate precursor product ion couples improving the capability in analyte identification.
With these limitations in mind, we believe this study highlights the importance of considering the measurement properties and instrument content in selecting HRQL measures for clinical trials.
Focus group discussions were carried out with youth to test whether the mental health constructs in selected instruments were comprehensible and linguistically and culturally meaningful.
The fourth surveys the instrument trade from 1785-1900 in selected American cities, while the fifth lists notable American collections now in existence.
As well as established and nationally validated measures, some new instruments are also being 'trialled' in selected centres.
Since 2003, the U.S. preventive services task force highlighted that the Mini-Mental State Examination (MMSE) was the best-studied instrument to screen cognitive impairment in selected patients with cognitive impairment [ 1].
The orbitrap mass spectrometer(26) is a high-resolution instrument, and it was possible in selected ion monitoring mode to unambiguously identify both homozygous and heterozygous sickle cell disease (Δ m 29.9745 Da).
Amino acid isotopologues were analyzed by an ISQ GC/MS instrument (Thermo Scientific, Waltham, MA) operating in selected ion monitoring mode (SIM) with a DB-5 column (30 × 0.25 mm i.d., Restek, Bellefonte, PA) using a ramp profile of 100 °C for 4 min, then 100 200 °C at 4 °C/min, and then 200 300 °C at 10 °C/min with a helium carrier gas flow rate of 1.2 mL/min.
They were trained for two days and the instruments were piloted and pre-tested in selected sub-districts.
The instrument included a question about employment in selected health care occupations and an open text field to record other occupational information.
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