Sentence examples for instrumental target from inspiring English sources

Endothelial cell-cell junctions have indeed emerged as an instrumental target involved in the vasculature defects observed within the tumor microenvironment.

They wrote that "the ways in which status can increase risk have been largely ignored and we identify a new pattern of victimization," which they call "instrumental targeting".

Importantly, in the case of mir-376a-5p mir-376a-5p mir-376a-5p3p and mir-376b-5pthe edited nucleoside resides in the seed region, which is instrumental in tandeting mir-376-3p mir-376-3p mir-376-3pd thereditedlead to anucleosidetaresidesectrum.

Tinchy Stryder)" Alias "Gladiator" Danny Weed "Creeper" Low Deep "Straight Flush" Dizzee Rascal "I Luv U" Wiley "Where's My Brother?" Jammer "Murkle Man" Musical Mob "Pulse X" Jon E Cash "Do It" Wiley "16 Bar Rally" Skepta "Tingles (instrumental version)" Target & Riko "Chosen One" Kano "P's & Q's" Sharky Major "This Ain't a Game" Tinchy Stryder "Move" Wonder feat.

Some closely related miRNAs are grouped into families by virtue of containing identical seed sequences (the first 6-8 nucleofides of their mature 5' ends); miRNA seeds are instrumental in target mRNA discrimination [18] and so individual miRNAs grouped into the same family are believed to be functionally equivalent [19], [20].

They often provide the first step for therapeutic intervention and are instrumental for target validation.

The definition becomes instrumental in targeting specific groups and communities.

Moreover, UL141 has also recently been shown to be instrumental in targeting the alternative DNAM1-activating ligand, CD112 (Prod'homme et al., 2010).

It prevents the subsequent aggregation of misfolded proteins and it is instrumental in targeting them for degradation when the above mechanism fails [ 30].

Understanding insulin secretion and its regulation mechanisms in vivo as well as being able to measure β-cell mass over the disease progression is instrumental for drug target screening, validation and for evaluation of therapeutic strategies.

Further elucidation of these differences will be instrumental in designing targeted regimens for the treatment of localized and advanced prostate cancer.