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Therefore, the solid-phase platform presented here has proven instrumental for preparation of composite heterobifunctional molecules with defined 1 1 stoichiometry.
Simplicity and versatility should prove this methodology instrumental for preparation of bispecific ligands, as well as for high-throughput screening of bispecific combinations, before proceeding to synthesis of lead candidates via recombinant engineering or chemical cross-linking.
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The method for preparation of samples, standard solutions, and quality controls as well as the instrumental analysis was previously described (Janjua et al. 2008) and used with the following modifications.
Experiments in kinetics, thermodynamics, and electrochemistry using instrumental methods; preparation and characterization of inorganic compounds; solids; some computer applications.
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The peculiar regulatory mechanisms, which may include adaptive changes at the level of the receptors, G proteins, and AC, are instrumental for the necessary physiological adjustments during prenatal life and preparation for the postpartum period.
Patient registries are instrumental for medical research.
4. * 8 02)—Instrumental for the first half.
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