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A powerful and versatile high throughput assay based on LC-MS allowed the simultaneous detection of primary and secondary oxidation products, which was instrumental for identifying variants with a strong preference for the terminal oxidation of palmitic acid.
3D cell culture models are slowly revealing how tissue architecture can dramatically influence how a cell responds to exogenous stimuli to modify its apoptotic behavior and hence should prove instrumental for identifying novel cell death pathways.
GWAS findings have been instrumental for identifying the genes and pathways serving as genetic trigger points that predispose to psoriasis [12,20,93].
Patient survival and metastasis development have been shown to be associated with certain CNAs [1] [7] and, by relating patterns of CNAs with survival, gene expression, and disease status, studies about copy number changes have been instrumental for identifying relevant genes for cancer development and patient classification [1], [2], [10].
The germline restricted vasa expression pattern, first demonstrated in Drosophila, has been instrumental for identifying germ cells in many animal species.
Given the very large HCMV proteome, extensive collections of HCMV deletion mutants are instrumental for identifying unrecognized interfering factors and pinpointing responsible HCMV genes.
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Health inputs are generally endogenous to health outcomes, and prices of health inputs are the most common instrumental variable for identifying estimates of the causal effects of health inputs.
IMS is an instrumental technique for identifying compounds and determining their concentrations, based on measurement of the velocity of ions drifting through air at atmospheric pressure under the influence of an electric field.
Homophily theory and SNA provided the theoretical and instrumental techniques for identifying theory, measures, and empirical models.
This paper describes an optimal instrumental variable method for identifying discrete-time transfer function models of the Box-Jenkins transfer function form in the closed-loop situation.
This paper describes optimal instrumental variable methods for identifying discrete-time transfer function models when the system operates in closed-loop.
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