Since β-IV spectrin and ankyrin G are instrumental in clustering voltage-gated sodium channels along axons (24, 25), we investigated whether expression of β-III spectrin and ankyrin R affected sodium channel expression.
A different way to derive AIMs is to identify SNPs that contribute highly to the significant PCs (PCAIMs), as first discussed by Paschou et al. SNPs that contribute heavily to the underlying axes of variation will be instrumental in clustering samples along population lines; it follows that these SNPs may be used to assign ancestry.
Topics include generalized method of moments, empirical likelihood, instrumental variables, bootstrapping, clustering, treatment effects, selection bias, difference-in-differences, qualitative choice, quantile regression, nonparametric methods, and semiparametric methods.
Similarly, P-cluster formation does not occur during reduction of the 1+ state to the all-ferrous state, implying that the intermediate states α1+0 and β1+0 (eq 1) are not instrumental in P-cluster formation.
We acquired data for one sample for five instrumental replicates; hierarchical cluster analysis (HCA) of all compound concentrations shows that these replicates are more similar than any other two sample spectra.
Second, the clustering algorithm was instrumental in generating good-quality clusters.
There is increasing recognition that the production of RNA transcripts from both orientations can produce coordinate regulation and since mammalian mRNAs that form sense-antisense pairs frequently exhibit reciprocal expression patterns [21] it is tempting to speculate that antisense transcription in the Hox Clusters is instrumental in establishing limits of gene expression.
On the other hand, an approach in which the hierarchical clustering is instrumental to find the overlapping community structure has been proposed by Lancichinetti et al. [56, 83].
Underneath his interest in 40-year-old, spaced-out German instrumental music — early Kraftwerk and Cluster and Popol Vuh — is a more purely strummy optimism.
The tDNA clusters might thus be instrumental in orchestrating the timing of DNA replication.
