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PRMs often do not need to be completely redeveloped for electronic administration, but additional testing for equivalence should be conducted, leading to some instrument modification [45].
Whilst a red target would be optimal, this is not possible using our instrument modification.
Further, our fixation target is blue due to the filter system used in the instrument modification.
However, these new techniques still have technical shortcomings with regard to instrument modification that must be overcome before their clinical application.
However, the 2 ms interval is nearly 2 orders of magnitude better than typical FSCV measurements of dopamine at CFMEs, and no instrument modification was required.
Chester et al. reported a modified RASS which could be utilized for daily delirium screening, but their tool incorporated an assessment of attention as part of the instrument modification [ 9].
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The data illustrate how each of these instrument modifications and newly developed methods can improve the EN by adding either sensors with complementary information or methods of sample pretreatment that enhance analytical performance.
All instrument modifications needed to enable this method were performed in-house and entailed changes to the instrument control code.
LR Sutherland conceived and supervised the study, and contributed to the instrument modifications and to the writing of the manuscript.
These instrument modifications make it plausible to detect minor changes in difficulty for IADL items positioned at the edge of the disability continuum, which can be used to signal the onset of progressive type disability in older adults.
The RASS instrument modifications at the beginning of the study and following the "initial" study, and qualitative and quantitative data showing general agreement amongst HCPs on the role of the RASS-PAL, provide evidence for construct validity.
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