Sentence examples for instructive pathway from inspiring English sources

Whether Notch is a permissive or an instructive pathway is not clear at this moment (Stockhausen et al., 2010).

The history of UCG development is instructive in designing a pathway to successful commercialization of the technology.

While these studies suggest an instructive role of activin/Nodal pathway in cardiogenesis, questions of cell autonomy and specificity remain unanswered.

Many signaling pathways provide instructive cues that promote development and drive morphogenesis of the otocyst into the architecturally complex inner ear.

Recent studies suggest that Notch signalling pathways are instructive in the development of LTi, ILC3 and certain NK cell subsets [ 10,32 35].

The main point we'd like to make with Figure 6 is that in addition to the traditional climbing fiber pathway, sensory-driven instructive signals can reach Purkinje cells via activation of a climbing fiber-independent pathway that modulates dendritic calcium and provides graded information about stimulus strength.

The instructive myogenic potential of the FGF pathway is also illustrated by the capacity of Htlca to induce myogenesis in tarsal segments otherwise devoid of muscle.

FGF signaling, mediated by Erk and Akt pathway activation, plays an instructive role on hairy2 expression with short-term/short-range characteristics.

This statement utterly relies on a tacit premise that assumes that the pathogenetic process depends on alterations in a discrete number of signalling pathways, thought to carry "instructive" biological "information".

The Notch pathway may also have more instructive roles, whereby signalling between neighbouring populations of different cells and induces the adoption of a third cell fate at their border, establishing a developmental boundary [ 14, 15].

In the assessment of any such potential scenarios, it may be particularly instructive to analyze the structure and functions of signaling pathway components identified in unicellular organisms that are closely related to metazoans [ 8].