There were also instructive interactions between the above mentioned factors.
These mesenchymal-epithelial instructive interactions are also responsible for the integrity of the prostate gland.
The functional importance of the instructive interactions between the epithelial cell compartment with the surrounding extracellular milieu has long been recognized in the intestinal tract [ 31, 32].
Future studies will be aimed at unraveling which are the temporal-spatial characteristics of RWs and their "instructive" or "permissive" interaction with molecular factors [28], [29].
A role for stromal cells in carcinogenesis has been suggested from studies of embryological development where instructive and permissive interactions, along with genetic factors, are required for programming and maintaining epithelial structure and function.
A particulary instructive observable is the interaction base pairing matrix, given by (10) Clearly, π i, k measures the probability that a pair of nucleotides (i, k), located on different strands, is contained in an interaction region.
On the other hand, we have shown that a model based solely on nearest-neighbour interactions, although instructive, is too simple to predict binding energies accurately.
However, we feel that to highlight the significance of sequence and structure in the continuum and to better understand the dynamics of protein DNA interactions it is instructive to distinguish between these two conceptually distinct landscapes, even though transitions between the two are smoothly connected in time.
Direct visualization of changes of photoreceptor morphology induced by infiltrating microglia using live-cell imaging will be instructive in further understanding microglia photoreceptor interactions.
While the CTB/GM1 system is instructive for studying multivalent ligand/receptor interactions in the context of fluid membranes, we wanted to validate our technology for studying various other types of membrane components.
