Exact(2)
Such instructive functions by the Rb family during cell fate determination may no longer be required once a cell becomes committed to a specific lineage, and the major function of Rb in committed cells might be to allow proper cell cycle exit and survival; a function that can be bypassed by survival factors or hypoxia.
During that Cultural Revolution, medical schools ceased their routine instructive functions and no new students were admitted between 1966 and 1970.
Similar(57)
To find out whether the bi-functional nature of BMs has an instructive function in organizing the tissue architecture of the developing nervous system, segments of human BMs were inserted into (a) the parasomitic mesoderm of chick embryos, intersecting with the pathways of axons and neural crest cells, or (b) into the midline of the embryonic chick spinal cord.
The rules were extracted in forms suited to the instructive function of the interface.
Restoring CTCF reinstates proper architecture on altered chromosomes, indicating a powerful instructive function for CTCF in chromatin folding.
Of course, the instructive function of school is still important, but, at the same time, the school has the role to regulate the social behaviours, by educating the emotional responses and developing students' social abilities.
Our results suggest that dopamine plays an instructive function in aversive learning, possibly conveying information about punitive stimuli.
Results of the present paper indicate that endogenous OA would accomplish the instructive function in the appetitive learning, but no data suggests yet which amine would achieve such a function in the aversive learning, although dopamine can be considered a candidate molecule from previous studies in insects [6] [10], [13].
The second assumption ascertains that each endogenous amine has a double action: on the one hand, it would mediate the reinforcement signal throughout training, i.e., an instructive function (sense [38]) and, on the other hand, it could interfere with the opposite learning when there is temporal coincidence between the amine release and the consolidation phase of the opposite learning.
Together, countless studies in a variety of model organisms support the concept that the ECM, and specifically FN, has an important and instructive function in early embryogenesis.
In some cases, DSXF and DSXM are antagonistic, but in other cases, both have a context-dependent instructive function (reviewed by [ 77]).
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