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Our findings are also of considerable relevance for normal hematopoiesis, as it remains disputed whether key cytokine receptor signaling pathways mediate critical in vivo functions in blood lineage development through purely permissive rather than instructive actions (Enver and Jacobsen, 2009).
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Access to Postmasters' roof is birds-only during the run of the show (it can be viewed on a live video feed), but there's plenty of delightful and instructive action once you walk out the door.
The latter exert a primarily instructive action to determine the actual shape of the newly-formed connections [1].
We reveal that SHH establishes a permissive state for FGF-instructive action on hairy2 expression through fine-tuned Gli3-A/Gli3-R activity.
In the course of our analysis we also uncovered that FGF and SHH pathways present distinct temporal and spatial signaling properties on hairy2 expression in the distal limb, noticeably consistent with what would be expected for an instructive and permissive action, respectively.
The analogy with action is instructive.
It is also instructive to see the action of the netsplitter procedure in an explicit network diagram.
One attempt to do so, a boycott of Nestlé as part of the Baby Milk Action campaign, proved instructive.
To study the great critics in action is incomparably more instructive than to read theoretical manuals.
Instead, these results suggest that SHH is creating a permissive condition defined as Gli3-A/Gli3-R>1 (sectionvious section) for the action of a distinct, instructive signal emanated by the AER on hairy2 expression.
So-called smart meters provide an instructive case study of this paradox in action.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com