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The phrase "instruction upon" is not commonly used in written English and may sound awkward.
It could be used in contexts where you are referring to guidance or directives given on a specific topic or situation, but it is better to use more standard phrases. Example: "The teacher provided instruction upon the new curriculum changes during the meeting."
Exact(2)
Grant recipients received the 5-day summer academy and a limited amount of additional resources for the development of integrated STEM curricula and instruction upon request.
Each couple had but one instruction upon greeting each other for the first time: to kiss.
Similar(57)
In fact, one of the first instructions upon installing iTunes is to 'import your favourite CDs with just one click'.
Going up to the penthouse, an elevator operator told us, in a serious tone, that we would be given instructions upon exiting on the 10th floor.
"Treating refugee women 'the same as Greeks' means speaking to them in Greek, giving them no option but male obstetricians, not translating for their medical instructions upon exit from hospital, and not taking into account the conditions they will face right afterwards.
They generate the task output by performing the instructions upon the received items.
Our methods included developing a day of surgery plan for teaching patients their discharge instructions upon arrival, creating on-line teaching videos, and revising post discharge pain medication instructions.
Instructions upon virtue spaces advance players toward the goal while those upon vice spaces force them to retreat.
Although aware of this plan when he took command, Mendizabal chose to ignore the instructions upon arriving on the north bank of the Guadiana on 5 February.
Instructions upon spaces depicting virtues move the player closer to The Mansion of Happiness while spaces depicting vices send the player back to the pillory, the House of Correction, or prison, and thus, further from The Mansion of Happiness.
We, the freeholders of the town, have delegated you the power of acting in our public concerns, in general as your prudence shall direct you, reserving to ourselves the constitutional right of expressing our minds and giving you such instructions upon important subjects as at any time we may judge proper.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com