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We took into account leftover medication of former refills and instructed treatment interruptions as described previously [ 42].
From the medical files of participants, we obtained information about sex, age, HIV transmission route, immigrant origin (country of birth outside the Netherlands), prescribed ARV medication, type of ARV regimen (NNRTI based, PI based, NRTI based), instructed treatment interruptions, prior virological failure since starting cART, and plasma viral load results.
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The Primary Investigational site is responsible for the patient data follow-up: patient consultations, instructing, treatment change or referencing to the general physician.
To measure caspase-3 activity, cells were harvested and fixed with Cytofix/Cytoperm solution (BD Biosciences, Franklin Lakes, NJ, USA) as instructed after treatment with Dox for 9 days and then stained with fluorescein isothiocyanate-conjugated rabbit anti-active caspase-3 monoclonal antibody (BD Biosciences).
Subjects were assigned to one of three treatment groups (National Acupuncture Detoxification Association [NADA] AA, AA at sham points, or treatment setting control) and were instructed to attend treatment sessions for 3 days.
Traditional classifiers and modern genomic tools allow the classification of breast cancer into subtypes that instruct its treatment that has become extremely different from one type to the other and from one patient to the other.
Patients need to be better educated on the causes and treatments available for CKD and instructed that medical treatment is essential for survival in life with CKD.
Patients with antihypertensive medication were instructed to continue treatment.
They were sent the test results by mail, and were instructed to seek treatment from gynaecologists or general practitioners.
The patient was instructed to receive treatment for a minimum of 24 months after the first negative sputum culture.
Owing to the non-interventional design of this trial, physicians were not instructed on any treatment decisions including dosages of vinflunine, tumor assessments, AE-management and concomitant medications.
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