In 1C11 cells, PrPC instructs the expression of the two immediate-early genes Egr-1 and c-fos.
How might mitochondria generate a signal that could instruct the nucleus to upregulate the expression of mitoferrin?
We found a correlation between the level of aggressiveness of the BRC epithelial cell assayed and their capacity to instruct immune cells to modify the expression of genes often reported to favor tumor growth.
Next, we assessed whether derepression of stem and progenitor cell genes in mature cells might affect the expression of the key transcriptional regulators that instruct and orchestrate granulocytic or erythroid differentiation (such as C/EBPα or Gata1).
The expression of specific Hox genes at specific times instructs cells in the developing embryo to adopt different fates according to their position along the anterior posterior (head to tail) axis.
Is it the expression of the mother?
Underlying the segmental organization of diversified GABAergic neuron development are organizational signals in the dorsal ventral and anterior posterior axes that instruct expression of transcription factors in distinct and overlapping patterns (Puelles, 2007; Nakamura et al., 2008).
