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HIV-negative patients are likely to reactivate a latent infection from decades ago, whereas HIV infected patients, in whom disease progresses rapidly, are likely to reactivate an infection acquired more recently following community or institutional transmission.
The usefulness of molecular typing was also confirmed in several epidemiologic investigations of HIV-associated multidrug-resistant TB outbreaks in hospices, hospitals, and prisons during the late 1980s and early 1990s and provided compelling evidence of institutional transmission (10– 10).
This plan was ambitious, yet initially naive about the full extent of the effects on TB incidence due to HIV infection; multidrug resistance; institutional transmission of M. tuberculosis; and the time lag for the development of new technologies for more effective prevention, prompt diagnosis and detection of drug resistance, and superior treatment of TB.
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Public health efforts to control and prevent norovirus illness have focused on rapid outbreak detection and source identification and control of transmission in institutional settings.
Epidemiologic investigations of these and other outbreaks have demonstrated that previous treatment for TB and transmission in institutional and community settings are important risk factors in MDR-TB development [ 10- 15].
Health worker uncertainty and institutional cultures of verbal transmission of information and practice guidelines may explain the difficulties in some facilities to institutionalize the use of regularly documented information and to develop or use written protocols and standard operating procedures.
Understanding better the burden of disease that is food-borne, and the relationship between virus circulation in the community and transmission in institutional and healthcare settings, is crucial for developing appropriate control strategies.
We utilized a unique opportunity provided by an unrecognized SARS patient who was the only known source of infection for a large cluster of secondary cases in an institutional setting to examine the transmission patterns of this novel disease.
In several instances, rodent control measures have interrupted disease transmission and halted institutional epizootics (4 ).
By contrast, the large familial networks of continental Europe act as the institutional anchor for property ownership and transmission, as well as for the formation of businesses and the provision of welfare.
Conveying and bringing this information to decision-makers and the public requires both efficient transmission of findings and institutional support for decision-making.
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CEO of Professional Science Editing for Scientists @ prosciediting.com