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It was approved by the institutional review board of the local institution (protocol no. 2013P000221/MGH), and written informed consent was obtained from each patient.
To review the incidence of postoperative bleeding in children with type 1 von Willebrand disease (VWD) who were treated with a single institution protocol.
As per our institution protocol, patients with sarcoma received neoadjuvant and adjuvant chemotherapy.
Patients were consented for chest drain insertion and pleurodesis with tigecycline as per institution protocol, after getting ethical committee approval.
The study followed the Declaration of Helsinki guidelines and was approved by the Human Research Ethics Committee of our Institution (protocol number 1318/1).
To replenish the patient's coagulation factors, he was given a dose of 25 units/kg (72 kg; 1,800 units) of 4 F-PCC based on institution protocol.
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Hypothermia was induced in all such patients upon arrival to the hospital per institution protocols regardless of study allocation, with the primary endpoint being survival and neurologic status at discharge.
The research protocol was approved by the institutional ethics committees of the participating Institutions (Protocol numbers 1175/08 and GPPG-HCPA 04 081), and recruitment of patients was done after signature of informed consent.
The study was conducted with ethical approval from these institutions (protocol nos. 932 and 4566, respectively).
In that report, all the HIV-positive patients were placed on HAART irrespective of CD4 cell count status according to the institutions' protocol.
Animals exhibiting signs of pain or meeting the endpoint criteria were euthanized immediately according to the accepted institution based protocol.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com