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The study was approved by the ethics committee of our institution (date of issue 1/11/2000, registration no. 035) and all patients gave their informed consent.
Data from the general reports were extracted to show data (institution, date purchased, price paid ($R), quantity and supplier) from the states of São Paulo and Paraiba for each of the 19 drugs.
All protocols in this study were followed in accordance with the guidelines of the Animal Care and Use Committee of our institution (date of issue: June 17, 2009; registration number: 0906170768).
All experiments were conducted in accordance with the Guidelines for Animal Experiments at our institution (date of issue: January 29 , 2010 registration number: A22-104-0), in accordance with Japanese law (no. 105), and in accordance with notification no.
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