Sentence examples for instead of the established from inspiring English sources

Thus, a paradigm shift in regulatory decision making was introduced for pesticides with endocrine properties: Instead of the established risk-based approach, a hazard-based approach is now required (i.e. only the proven presence or assumed absence of endocrine disrupting properties shall be decisive for a [non]authorization).

Instead of the established GBM cell lines, using surgically resected tumor tissues directly from GBM patients and passing them in animals will generate stable orthotopic GBM xenografts, which show oncogene patterns very similar to primary tumors of patients.

Why the reliance on the original code instead of the established methods of motif search and sequence alignment?

[F]FDG PET-CT has been used increasingly in metastatic MCT but at present there is insufficient data to state if it will be used instead of the established nuclear medicine techniques.

However, when a cell is dividing, these proteins switch to regulate both processes, but direct all the material to a new destination the newly forming membrane, instead of the established surface membrane.

This regimen was chosen instead of the established one (weekly PAC) for better patient convenience, while maintaining the same dose intensity of the established weekly regimen for both drugs.

Instead, the weakness of the established Canadian identity encouraged a plurality of them – not to mention a healthy flexibility and receptivity to change.

Together these data suggested that an internal weakly mismatched transplant is not ignored by a newly generating immune system, instead the location of the established graft determines whether the graft triggers CTL priming or tolerance.

(Of all existing MDRD formulae, we chose the MDRD4 equation as is was the most common one at the time when this study was started. Therefore, we used the earlier factor 186 instead of the later established value 175).

His decision to take his protege Conley (whom Redding and Walden had contracted directly to Atco/Atlantic Records rather than to Stax/Volt) on the tour, instead of more established Stax/Volt artists such as Rufus Thomas and William Bell, produced negative reactions.

As all scleroderma patients were prevalent cases, we validated their diagnosis checking that they met the classification criteria for SSc established by the ARA in 1980 [ 17] instead of the new one established in 2013 by the ACR/EULAR [ 18].