Sentence examples for instead of loss of from inspiring English sources

Thus, the relatively subtle somatic phenotypes reported for Sacytm1Lex/Sacytm1Lex mice [31] may be due to altered expression of a somatic sAC isoform instead of loss of sACt or sACfl.

This finding may be particularly relevant to consideration of SP4 as a candidate susceptibility gene for psychiatric disorders, as considerable evidence suggests that hypomorphic alleles, instead of loss of function, of multiple genes contribute to the pathogenesis of psychiatric disorders [44].

The use of PPD instead of loss of clinical tooth attachment (PPD + gingival recession) is well reasoned in this context because measurements of clinical attachment loss do not reflect the inflammatory area of soft tissues surrounding the teeth.

Asset management reported its first pretax profit since the last quarter of 2007, mainly from gains instead of losses from its real estate-heavy investment portfolio and a decision to sell its retail money management business.

Mutant FUS is therefore likely to cause ALS through a dominant gain-of-function effect, instead of a loss-of-function effect through titrating and reducing the WT-FUS function.

These findings also complement other reports that single sodium channel mutations can result in multiple phenotypes giving rise to an 'overlap syndrome' as well as unique isolated phenotypes in which a mutation expected to result in a gain-of-function results in phenotypes that include changes suggestive instead of a loss-of-function.

Unexpectedly, MG 132 did not reverse the GLP-1-induced suppression of iNOS expression but instead induced loss of iNOS protein and hence proteasomal inhibition did not prevent but stimulated degradation of iNOS, suggesting other control mechanisms regulating the cellular balance of this protein.

Assuming that argos expression in veins represents a faithfull readout of EGFR signaling, we observed instead a loss of EGFR activity in the absence of hrs and stam at the pupal stage.

Instead, surprisingly, loss of Sec8 triggered an increase of NMJ size during larval development.

If the displaced disk material is not calcified, it cannot be clearly seen and instead a loss of epidural fat or displacement of the spinal cord may help to identify the location of displaced IVD material [ 5, 27].

But not only did we not observe any gain of Notch signaling effects, we instead observed loss of Notch signaling phenotypes in a proportion of the animals that worsens as we increase the Serrate gene dosage.