On the other hand, in the group of studies that have found no superiority of FES over conventional therapy, there are good quality articles that have mostly used those assessment methods that measure function or activity instead of impairment.
To ask the patients to rate difficulty, activity limitations according to International Classification of Functioning, Disability and Health ICFF) [ 30] instead of ability (impairment), as common in orthopaedic rating scales, provides a possibility for the patient to individualize the importance of each item.
In the analysis of ICU-AW, it may be more appropriate to use a functional measure instead of an impairment-specific tool, as function is a manifestation of a number of different qualities, such as strength, cognition, alertness, balance, and so on.
This conceptualisation challenges any notion of SLI as a single syndrome and also suggests that we may need to analyze it in terms of dimensions of impairment instead of looking for discrete subtypes.
These data provide two insights: Firstly, reduced whole blood aggregation in septic shock was independent of molecular evidence of reduced actin-myosin contraction (no change in myosin LC20 phosphorylation), instead suggesting impairment of other elements of platelet function such as adhesion or granule secretion.
Instead of monitoring some particular impairment or a specific biological target of oxidative stress, it is preferable to examine the global effect of a stress, which is revealed by a loss of cellular homeostasis.
However, this analysis did not rule out the possibility of a motor impairment, instead of hearing loss, as the primary cause of the reduced startle response.
Instead of scaling the cognitive impairment scores post-estimation, we performed an equivalent linearly scaling of the ADAS-Cog item parameters to enforce these measurement scales for estimation of memory, language, and praxis impairment.
In fact, the main purpose of our study was to assess how well the quantitative CT measurements can explain the lung function impairment, instead of testing for the optimal method.
