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On the other hand, in contrast to frequent (del 8p in B-cell lymphoma, del 8p) is infrequent in NK/T-cell lymphoma [35], and hence, in NK/T-cell lymphomas, miR-124-1 might be inactivated by biallelic hypermethylation instead of deletion together with gene hypermethylation.
Because the reduction of the genome size of G. aurea occurred rapidly, it was likely driven by selection, instead of deletion bias in the mutation process that is thought to be one of the major determinants of genome size [ 45].
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Nevertheless, as in Arabidopsis, the differences in length were mainly due to shortening in the C-terminus instead of deletions within the protein primary sequence.
Although we do not completely rule out the possibility that the reduced distances between genes actually resulted from translocation of DNA segments instead of deletions, it is very unlikely, as gene order is highly conserved in Salmonella and DNA translocation does not generally occur except those mediated by recombination of rrn genes or other repeated elements.
Surprisingly, instead of the deletion, an interstitial duplication of the same region was detected: arr[hg19] 6p25.1p24.3(4,745,144-10,384,769)x3 (Fig. 2a).
Retroviruses mutate rapidly, and it is possible that some subtypes adapted to the insertion allele instead of the deletion allele.
It would be nice to have at least one experiment performed with an R-K mutant instead of the deletion construct.
Instead of this deletion of observations we propose fitting an 'extended RVSOM' where separate and additional variance components ω j 2 ≥ 0 are allowed for all of the outlying trials.
With an expected attrition rate of 30%, multilevel regression analyses are more appropriate than repeated measures ANOVA, because they allow all data available to be used instead of listwise deletion.
In addition to this expected pattern, we also found such variants represented as typical SNPs (and not indels), but with missing genotypes present at one locus instead of a deletion state.
Instead of deleting a single gene, one can simultaneous delete d genes (d-deletions).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com