Sentence examples for instead of activation from inspiring English sources
It was speculated that instead of activation by large depolarization, hardly attainable in T-cells, Cav channels may be activated due to their clustering and interaction with PKC [ 287].
In this context, the spacer promoter transcript functions in rDNA silencing instead of activation.
Furthermore, predictions made assuming the wrong regulatory mechanism (inhibition instead of activation) do not match experimental results regardless of circuit permutation.
Measuring repression instead of activation avoids the complications of non-linear interactions between the transcription factor and RNA polymerase which differs at each promoter.
Expression below or above the optimal stoichiometry can therefore result in inhibition instead of activation, as reported for overexpression of KSR1 in human embryonic kidney cells [ 27].
In such cases it may be more appropriate to refer to persulfate decomposition instead of activation, and this is the convention that is followed throughout this manuscript.
Our analysis predicts 86% (31/36) of the connections as significant based on the microarray dataset; however, four are considered inhibitory interactions instead of activations, suggesting possible feedback loops between Pax6 and Ngn1, between Satb2, Ngn2 and Nhlh1, as well as between NeuroD and Etv1 (Additional file 6).
In breast cancer cells, rapalogs such as RAD001 can induce MAPK activation instead of AKT activation.
In Model 1 both molecules, A and I, are regulated by the external signal, which is proportional to cAMP concentration S. With rate constants k a, k- a, k- i and, the dynamics of A and I are given by: In Model 2 the inhibitory molecule I is activated through the indirect action of activator A instead of direct activation by sensing of ligand binding, giving: where is a rate constant.
Counter-intuitively, we observed that SL-LPS significantly suppressed ERK activation in neutrophils, instead of activating ERK.
These results indicate that, instead of direct activation of HSCs by PA, HSCs were indirectly activated by PA via PA-elicited paracrine effect of hepatocytes.
