When he called Verio to ask why his entire network had been unplugged instead of the sole offending site, he said, a Verio lawyer told him that the Thing had violated its policies repeatedly and that its contract would be terminated.
There have been a few innovations since then, such as adding a town hall-style debate to the mix and opting for a sole moderator instead of a panel of journalists.
To that end, he said, he'll try to make promoting and fostering L.A.'s arts and culture offerings "a value for the entire city government" instead of the sole domain of the Department of Cultural Affairs.
This suggests that the antimalarial effect of ubiquinone analogs is rather due to either additional inhibition of the downstream Complex III or simultaneous inhibition of all enzymes providing ubiquinone with electrons (including dihydroorotate dehydrogenase), instead of the sole inhibition of succinate dehydrogenase or NADH dehydrogenase.
One representative of these bacterial sequences (Aquifex aeolicus) has indeed been deeply studied and shown to adopt an archaeal PYC structure (i.e., two types of subunits instead of one sole polypeptide) and to actually carry out the PYC function [ 38, 42].
Instead of a single output node that is the sole read-out for the system, one can develop read-outs for each node, e.g. measuring the phosphorylation state of a protein.
This broke from the programme's tradition by using a subplot with more developed characters – instead of being the sole centre of attention, Bean here interacted with a suburban Californian family he stayed with while overseeing the transfer of Whistler's Mother to a Los Angeles art gallery.
The changes in these standard settings included pH varying between 5.5 and 7.5, pO2 at levels of 5%, 20%and50%0%, use of 50 mM glucose or mannitol instead of methanol as sole carbon source and 16 mM glutamine as sole nitrogen source, and application of osmotic stress by addition of 300 mM sorbitol or 160 mM NaCl.
Using a single test score as the sole measure of achievement instead of a student's yearlong performance in class leads to what Isaacs and others have labeled "perverse incentives," including disregarding whether students can actually apply what they have learned.
That is, a joint ownership of the curriculum instead of the traditional sole ownership model.
