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We also solved all instances of Table 1 by the heuristic algorithm H1 of Section 3.3.
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Four potentially optimum solutions were identified: all four reconstructions postulated 32 codivergence events (equivalent to 16 instances of cospeciation) (Table 6, Fig 3B).
We tested the reported epistasis between six SNPs and the PTPN22 rSNP76601 SNP according to the original model: multiplicative interaction (evaluated as the interaction term of a logistic regression or its equivalent RORi between the minor alleles following dominant inheritance [ 22]. These analyses did not replicate any of the six instances of epistasis (Table 3).
In this list it was important not to favour comebacks in high-profile events over more startling instances of the tables being turned in lesser contests.
The load_table_model command reads data from a file or crate and assigns it to an instance of the table model class that can be combined arithmetically with the source model.
For most cases, the load_table_model function should be used to create an instance of the table model; it will read in data from a file and create a tablemodel component for you.
Reported instances of artificial recombination (Table 3 in Ref. [7]) were further tested with EMMA following the same logic (ESM7).
Furthermore, all of the m4C and m6A motifs identified were methylated in 98-100% of the instances of each motif (Table 1), suggesting that none of these were false positives generated by an inappropriately low threshold.
C4.5 correctly classified 81% of instances (Table 4) with F-measures of 0.87 and 0.67 respectively for the classes "CREB-regulated" and "NOT CREB-regulated" respectively.
Overall, collateral responses were observed in 39% (233/590) of possible instances (Supplementary Table 2); of these 49% (115/233) were associated with only a 1.5-fold change in IC90.
For instance, the second row of Table 2 shows the results for AF repeated four times.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com