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In several instances, expression of miRNAs was shown to have a function in tumour biology.
In most instances, expression of collagen types I and II, aggrecan, COMP and Sox9 were significantly higher in D21 scaffold constructs compared to P3.
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For instance, expression of the tumor suppressor Gprc5a prevents constitutive p65 nuclear localization and NF-κB activation [29].
For instance, expression of GsWRKY20 in Arabidopsis enhances drought tolerance and regulates ABA signaling [ 30].
For instance, expression of miR-146a was significantly increased in pSS patients compared with healthy controls [39].
For instance, expression of some stroma-specific genes appeared to be correlated with patient prognosis [ 2, 25].
For instance, expression of gelatinases, a class of matrix metalloproteinases, did not correlate with the metastatic/invasive potential of B16 melanoma variants [ 7, 8].
For instance, expression of ZEB1 a downstream target of SNAIL1 is also up-regulated in HDAC1 null teratomas (SL and CS, unpublished data).
For instance, expression of many other cytokines and molecules involved in activation of dendritic cell function also appear to be regulated by NS1 (30 ).
For instance, expression of TNFSF5 (CD40LG) has been mainly reported in CD4+ T cells, facilitating the activation of CD8+ T cells [ 18].
Hormones can modulate the activity of glutathione S-transferases; for instance, expression of GSTA-encoding genes is inhibited by thyroxin and triiodothyronine [ 45].
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