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For instance, elementary modes and extreme pathways have been used to exhaustively describe the independent metabolic routes occurring in newly reconstructed models, often sorted by metabolic function (Schilling & Palsson, 2000; Van Dien & Lidstrom, 2002; Papin et al., 2002).
In many instances, PCA modes 1 5 of the ncv2 and ncv3 trajectories involved alterations in the backbone dihedral ψ angle of ligand-binding residue residue Glu/Gln63, and ligand release was approximately coincident with sustained changes in this angle in both the ncv2 and ncv3 simulations (Supplementary Figures 7(a) and 7(b)).
In general, vessel co-option is only one of many related mechanisms that may explain resistance to antiangiogenic treatment, as for instance, other modes of tumor vascularization (intussusception, vasculogenesis, and VM) 13, alternative proangiogenic factors 42, vascular maturation 43, activation of autophagy 44, or recruitment of myeloid-derived suppressor cells 45.
In some instances, the mode of the post corresponded to certain thematic content categories for posts.
This is partly due to the symmetries of his technique for instance the modes of limited transposition do not admit the conventional cadences found in western classical music.
In most instances, the mode of action is through the cellular conversion of a precursor compound to an active triphosphorylated form that might inhibit cellular or viral DNA synthesis, interfere with nucleotide metabolism, or become incorporated as a toxic lesion into the DNA of rapidly dividing tumor cells.
I'd go even further and suggest that Apple might be thinking long-term about how this could apply broadly to all iOS devices – the 6 Plus already behaves a lot like an iPad when used in landscape mode, for instance, and it's not hard to envision it supporting a split-screen interface given the flexibility of a single-column vertical scroll mechanism for apps like iMessage or Notes.
For instance, Portrait Mode has been improved and the Photos app is getting better at showing you personalized recommendations.
Instances where the mode classifier performed well reflect unequal distributions of sensitive and resistant segregants.
Analysis, for instance, predicted three modes of instability that can develop in extending the jet, of which two are axisymmetric.
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