Exact(6)
For instance, the activity of TF CREB depends on a number of post-translational modifications, most notably, Ser133 phosphorylation by Protein Kinase A [ 8].
For instance, the activity of GS is suppressed via feedback inhibition (FBI-GS) by the product glutamine and by AMP [ 1].
At these concentrations, the total area of the particles surface would reach the ability to interfere in the normal chemical reactions of the organisms, such as for instance the activity of key enzymes.
For instance, the activity of endothelial nitric oxide synthase (eNOS) in producing nitric oxide in endothelial cells absolutely requires CaM [ 33] and it appears to also require Ca2+ to sustain elevated level of activity [ 34].
For instance, the activity of the A217G mutation toward allyl glycidyl ether was lower than that of the wild type by a factor of 33, whereas the A217V mutation increased activity toward this substrate 6.6-fold.
For instance, the activity of a T. cas wg CRM is like that of the wg_Δwg enhancer (Von Ohlen and Hooper 1997) (Tcas_wg_1; fig. 5 a. A;), whereas a T. cas Dichaete CRM recapitulates postblastoderm expression driven by the D_D/fsh_O-E enhancer (Ochoa-Espinosa et al. 2005) (Tcas_D_1; figs. 5 a. C and 4 a. D).
Similar(54)
For instance, the activities of mTORC1 are regulated by energy status, hormones, growth factors, amino acids, glucose, and oxygen [ 72, 74], while those of mTORC2 can be activated by the growth factors and amino acids.
Wnt signals are context-dependently transduced to the canonical and noncanonical pathways based on the expression profile of WNT, SFRP, and FZD genes for instance, and the activity of cytoplasmic WNT signal regulators.
An abnormal result for one hormone should be treated with caution; the defect of cytochrome P450 oxidoreductase deficiency, for instance, affects the activity of two enzymes and corticosterone and progesterone should be measured as well as 17-OHP.
In instances where the activity of a TF is reported to be dependent on interaction with another protein or multi-subunit complex, the protein protein interaction (PPI) is annotated using 'transcription factor binding' MF GO terms as shown in Figure 1B (terms shaded yellow).
Several aspects of the immune response could also be affected in an opposite fashion to those in the T1D study, for instance, the activity and functioning of activated Th1 and T regulatory cells (CD4+CD25+) but at the moment, the relevance and the role of this potential phenotypic data in the pathogenesis of MS is unknown.
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