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In a later phase, once LIDs have been established, hyper-activation of PKA/DARPP-32 may become sufficient to maintain their expression independently of ERK, most likely by short-term regulation of neuronal activity through, for instance, regulation of the state of phosphorylation of GluR1 and other ion channels.
For instance, regulation of synaptic plasticity and function has been shown to be associated with caspase-3 activation.
For instance, regulation of kinase autophosphorylation by activation segment exchange between two adjacent catalytic domains was initially observed in the crystal structure of the kinase CHK2 [12].
For instance, regulation of the protein stabilization/degradation or ribosomal stalling during translation (which would produce RFPs but not functional protein product), could explain the lower correlation observed.
This does not rule out a role for global regulation of the synthesis rate, via, for instance, regulation of the overall GS levels at a transcriptional level.
The choice between both system modes should be cell type dependent, for instance regulation by the JAK/STAT3 pathway and resulting Bcl-2 expression control in the non-apoptotic state is known for hematopoetic cells [ 8].
Similar(52)
Yet the law is still not quite complete.For instance, regulations for the distribution of revenues must still be drafted.
In India, for instance, regulations are an outcome of a mix of "rational" economic and legal arguments as well as the country's history and political climate.
In many instances regulations and government policy proved to be costly and inefficient ways to address the identified problems.
For instance, "negative regulation of apoptotic process" is enriched in cluster I, while "negative regulation of cell proliferation" is enriched in cluster III.
For instance, posttranslational regulation can be more important for a particular regulator, or individual genes can hybridize less than optimal on the microarray, leading to expression signals that are too noisy for detailed interpretation.
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