Instead, Mr. Castro has cracked down on dissidents in recent months, executing three who hijacked a ferryboat and arresting dozens in the most severe instances of political repression in Cuba in decades.
Conceptually, the action of HDAC inhibitors leading to an increase in histone acetylation should induce expression of susceptible genes, but in fact, many instances of a repression of gene expression have been reported [ 25- 29].
For instance, forced repression of Oct4 and Nanog or overexpression of Cdx2 and Hras could divert mouse ES cells toward trophoblastic fates [8], [34], [35], [36].
For example, if a gene were silenced by epigenetic means for multiple generations (heritable RNA interference for instance, or repression of transcription by heritable changes to the chromatin or DNA methylation), the gene could become more prone to accumulate mutations in its DNA sequence, some of which could ultimately silence it genetically.
Just one more instance of the old modes of repression being alive and well in Egypt.
I found it a pleasure to read Robert McCrum on the English language's development in, for instance, the 14th century: "After centuries of repression, the recognition of 'Everyman' and the 'true commons' was... expressed in the simple English words that hold good still".
We did not find induction of thioester-containing proteins (TEPs) but rather repression, for instance of TEP-D (Supplementary file 2).
For instance, repression of human telomerase reverse transcriptase (hTERT) expression in breast and liver cancer cells was shown to be partly mediated by SIP1 [ 17, 18].
For instance, the repression level in the absence of DNA looping is 135 for WT1 and 2.3 for WT2.
Commitment to a neuronal cell-fate, for instance, involves the repression of gliogenic genes; the alternative scenario of glial differentiation, requires the inhibition of genes responsible for neuronal specification.
